The following is a compilation of some of the most important research in support of the Oral Systemic connection.
Bale/Doneen causal relationship article.
Periodontal Pathogen AA and its effects on endothelial cells.
Changes in clinical and microbiological periodontal profiles reklate to progression of carotid intima-media thickness.
Associations between chronic periodontitis/edentulism and risk of coronary heart disease.
Concordia study showing lower healthcare cost across the board for patients under periodontal maintenance.
Periodontal disease and Lp-Pla2 inflammatory biomarkers.
Periodontal disease and stroke risk.
Periodontal disease associated with heart attack risk.
Oral infections and vascular disease study (INVEST)
Periodontal disease and coronary plaque.
Oral pathogens in acute coronary syndrome thrombi.
Periodontal pathogens in carotid atheroma.
Periodontal pathogen (Pg) invasion of heart cells and endothelial cells.
Microbiological parameters in patients with acute myocardial infarction.
Periodontal disease and inflammation
Periodontolgy and cardiology consensus report
Periodontal disease and lung cancer.
Links between oral health and general health.
Periodontitis increases risk of first myocardial infarction.
Periodontal therapy and regression of carotid IMT score.
Coronary heart disease and tooth loss.
Oxidative stress and oral bacteria.
Periodontal disease and pancreatic cancer.
Periodontal disease and obstructive sleep apnea.
Periodontal disease and breast cancer.
Periodontal pathogen (Pg) and esophageal cancer
Oral pathogens disrupt immune response.
Periodontal disease and chronic kidney disease..
Periodontal pathogen (Pg) and arthritis.
Periodontal pathogens, osteoarthritis, and periprosthetic infections of knee.
Periodontal disease and diabetes.
Periodontal disease and low birth weight risk.
Periodontal disease and cognitive decline in Alzheimers patients.
Periodontal disease, cognitive impairment, and dementia.
Periodontal disease treatment lowers cancer risk.
Periodontal disease and venous thromboembolic disease.
Periodontal pathogens in coronary atherosclerotic plaque.
Periodontal Pathogen (Pg) interactions with human coronary artery endothelial cells.
Oral bacteria found in 90% of unhealthy heart valves.
Periodontal disease and pre-hypertension.
Periodontal pathogens linked to low HDL and high triglycerides.
Periodontal pathogens in carotid atheroma.
Cardiovascular and cerebrovascular disease secondary to oral infection.
Glomerulonephritis secondary to oral infection.
Bacterial endocarditis secondary to oral infection.
Periodontal pathogen (Pg) is the most abundant species detected in coronary and femoral arteries.
Periodontal pathogen (Pg) is involved in the pathogenesis of diabetes mellitus (DM).
Periodontal pathogen increases colorectal cancer mortality.
High Lp-PLA2 doubles risk for Alzheimers
Periodontal pathogens and oxidative stress.
Periodontal pathogens and rheumatoid arthritis
The use of phase contrast microscopy is useful in periodontal risk assessment.
The use of bleach as an oral antimicrobial.
History of periodontitis, diagnosis, and edentulism as predictors of cardiovascular disease, stroke, and mortality in postmenopausal women.
CANTOS study on targeting inflammation.
Periodontal disease and atherosclerosis: Strengthening the oral-systemic link.
Mouth bacteria linked to esopohageal cancer
Research may explain why gum disease is linked to heart disease.
Oral bacteria and colon cancer.
Gum infections and stomach cancer.
Oral bacteria and esophageal cancer.
Trends In salivary diagnostics
Advanced gum disease increases risk for lung and colorectal cancer
Studies link gum disease with pancreatic cancer
Poor dental health can increase diabetes risk
Dementia and Oral Spirochetes
We May Finally Know What Causes Alzheimers And How To Treat It
Comparison of Endotoxin Levels Found In Primary and Secondary Endodontic Infections
Impact of Endodontically Treated Teeth on Systemic Disease
Microflora of Endodontic Infection
Chronic Oral Application Of A Periodontal Pathogen Results In Brain Inflammation, Neurodegeneration, and Amyloid Beta Production In Mice
Oral Health And Blood Pressure
Candida Infection Can Reach Brain And Impair Memory
Does Periodontal Disease Drive Pancreatic Cancer?
Oral Microbiota Linked To Pancreatic Cancer
The Larkin Protocol